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REFLECTIONS

                                                                                                              Dyslipidaemia
     Dyslipidaemia Global Newsletter #7 2024




                  TABLE OF CONTENTS


            KEY ARTICLES                                        Welcome again to the Reflections Dyslipidaemia Global
                                                                Newsletter, where an international Scientific Planning
          RISK ASSESSMENT
                                                                Committee summarizes and provides expert commentary
          A focused update to the 2019 NLA scientific statement on   on the latest clinical and real-world evidence in the field of
                                                                                                              Dyslipida
          use of lipoprotein(a) in clinical practice. Koschinsky ML, et al.   dyslipidaemia. These articles are chosen based on their
          J Clin Lipidol. 2024 Mar 29:S1933-2874(24)00033-3.
                                                                significance to every day clinical practice. This newsletter
          TREATMENT                                             focuses on recent updates to risk assessment with
          Is there a role for earlier use of combination therapy?   lipoprotein(a), the earlier role of combination therapy, and
          Revankar S, et al. Am J Prev Cardiol. 2024 Feb 15:17:100639.  several articles on special populations such as young adults,
                                                                familial hypercholesterolemia, obesity, and people with
          SPECIAL POPULATIONS                                   diabetes. As with the previous newsletters, we invite you to
           Primary prevention of subclinical atherosclerosis in young   interact through links to short video commentaries from our
          adults: JACC review topic of the week. Devesa A, et al. J Am   SPC, links to videos or podcasts, along with hyperlinks to full
          Coll Cardiol. 2023 Nov 28;82(22):2152-2162.           articles for in-depth study and reflection.
          Familial hypercholesterolaemia in children and
          adolescents from 48 countries: a cross-sectional      Prof. Farnier (Chair)
          study. European Atherosclerosis Society Familial
          Hypercholesterolaemia Studies Collaboration. Lancet. 2024 Jan   SCIENTIFIC PLANNING COMMITTEE
          6;403(10421):55-66.
          Obesity, dyslipidemia, and cardiovascular disease: A joint   Prof. Michel Farnier        Prof. Augusto Lavalle
          expert review from the Obesity Medicine Association and      (France)                    Cobo
          the National Lipid Association 2024. Bays HE, et al. J Clin                              (Argentina)
          Lipidol. 2024 Apr 18:S1933-2874(24)00048-5. doi: 10.1016/j.
          jacl.2024.04.001. Online ahead of print.
                                                                       Prof. Miriam Sandin         Prof. Lourdes Santos
          Lipid-lowering in diabetes: An update. Chait A, et           (Spain)                     (Philippines)
          al. Atherosclerosis. 2023 Oct 6:117313. doi: 10.1016/j.
          atherosclerosis.2023.117313. Online ahead of print.

                                                                       Prof. Ahmed Shawky          Prof. Marcin Welnicki
             ADDITIONAL ARTICLES OF INTEREST                           (Egypt)                     (Poland)





    RISK ASSESSMENT


     A focused update to the 2019 NLA scientific statement on use of lipoprotein(a) in
     clinical practice.

     Koschinsky ML, et al. J Clin Lipidol. 2024 Mar 29:S1933-2874(24)00033-3.

     Since the 2019 National Lipid Association (NLA) Scientific Statement on the Use of Lipoprotein(a) in Clinical Practice was issued,
     there has been additional epidemiological data to clarify the relationship between Lp(a) and CVD risk reduction.


     This focused update by the NLA reviews the new emerging evidence on the role of elevated Lp(a) as a CV risk factor, provides
     recommendations on the candidates for Lp(a) screening, the measurement of Lp(a), and discusses treatment options.
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