Page 12 - reflections_dyslipidaemia_newsletter7_2024

REFLECTIONS
Dyslipidaemia
Dyslipidaemia Global Newsletter #7 2024

TREATMENT Dyslipidaemia

10. Comparison of effectiveness of high dose statin monotherapy with combination of statin and ezetimibe to
prevent cardiovascular events in patients with acute coronary syndrome: A systematic review and meta-analysis.
Damarpally N, et al. Cureus. 2024 Mar 10;16(3):e55922.
11. Statins use for primary prevention of cardiovascular disease: A population-based digitally enabled real-world
evidence cross-sectional study in primary care in Brazil. Santo K, et al. J Clin Lipidol. 2024 Feb 20:S1933-
2874(24)00025-4.
12. Lipoprotein(a) Blood Levels and Cardiovascular Risk Reduction With Icosapent Ethyl. Szarek M, et al. J Am Coll
Cardiol. 2024 Apr 23;83(16):1529-1539.

13. Oral strategies to target proprotein convertase subtilisin/kexin type 9 and lipoprotein(a): the new frontier of lipid
lowering. Norata GD, Tokgözoğlu L. Eur Heart J. 2023 Dec 21;44(48):5018-5020.

14. Plozasiran (ARO-APOC3) for Severe Hypertriglyceridemia The SHASTA-2 Randomized Clinical Trial. Gaudet D, et al.
JAMA Cardiol. 2024 Apr 7:e240959.
15. Bempedoic acid for Primary Prevention of Cardiovascular events in statin-intolerant patients. Nissen SE, et al.
JAMA. 2023 Jul 11;330(2):131-140.

ACRONYMS:
ANGPTL3, angiopoietin-like protein 3; AOMs, anti-obesity medications; apoB, apolipoprotein B; apoC-III, apolipoprotein C-III;
ASCVD, atherosclerotic cardiovascular disease; ASO, antisense oligonucleotides; ATP, adenosine triphosphate; BP, blood pressure;
CI, confidence interval; CV, cardiovascular; CVD, cardiovascular disease; DLCN, Dutch Lipid Clinical Network; FH, familial
hypercholesterolaemia; HbA1c, glycated haemoglobin; IDL-C, intermediate density lipoprotein cholesterol; IPE, icosapent-ethyl;
JAS, Japanese Atherosclerosis Society; LDL-C, low-density lipoprotein cholesterol; Lp(a), lipoprotein(a); Lp(a)-C, lipoprotein(a)-
cholesterol; LLM, lipid-lowering medication; Mab, monoclonal antibodies; MEDPED, Make Early Diagnosis to Prevent Early Deaths;
OR, odds ratio; PCSK-9i, proprotein convertase subtilisin/kexin type 9 inhibitor; SBP, systolic blood pressure; Simon Broome, Simon
Broome Diagnostic Criteria for Familial Hypercholesterolemia; VLDL-C, very low density lipoprotein cholesterol.

TABLE OF CONTENTS